Article Study offers clearer understanding of how obese people can sustain weight loss

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Maintaining a stable weight loss is the biggest struggle for obese individuals, yet new research from University of Copenhagen have allowed researchers new insights into the complex processes involved in obesity and especially weight loss in obesity. It is now possible to offer overweight people a clearer understanding of how to sustain weight loss.

"This study shows that if an overweight person is able to maintain an initial weight loss -- in this case for a year -- the body will eventually 'accept' this new weight and thus not fight against it, as is otherwise normally the case when you are in a calorie-deficit state," says Associate Professor Signe Sorensen Torekov from the Department of Biomedical Sciences and Novo Nordisk Foundation Center for Basic Metabolic Research

Maintain your weight loss

Twenty healthy, but obese, individuals followed an 8-week low-calorie powder diet and lost on average 13 % of their body weight. After the initial weight loss, the participants entered a 52-week weight maintenance protocol, which consisted of regular meetings with a clinical dietician with instructions on lifestyle changes as well as diet calendar tracking. In case of weight gain, the participants could replace up to two meals per day with a low-calorie diet product.

During the study period the participants completed three meal tests -- before weight loss, immediately after weight loss and after 52 weeks of weight loss maintenance, where blood samples were collected after fasting as well as postprandially and subsequently analysed.

"The interesting and uplifting news in this study is that if you are able to maintain your weight loss for a longer period of time, it seems as if you have 'passed the critical point', and after this point, it will actually become easier for you to maintain your weight loss than is was immediately after the initial weight loss."

"Thus, the body is no longer fighting against you, but actually with you, which is good news for anyone trying to lose weight," concludes Associate Professor Signe Sorensen Torekov.


Study offers clearer understanding of how obese people can sustain weight loss
 
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