World number eight Rafael Nadal is out of the US Open after losing a five-set, third-round thriller to Italian Fabio Fognini at Flushing Meadows.
Spaniard Nadal's 10-year run of winning at least one Grand Slam singles title was ended by the world number 32, who won 3-6 4-6 6-4 6-3 6-4.
It is the first time the 29-year-old - twice a US Open champion - has lost in a Grand Slam having been two sets up.
Fognini, 28, faces Feliciano Lopez of Spain in the fourth round.
BBC Sport - US Open: Rafael Nadal loses to Fabio Fognini in third round